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Jun Xia Selected Research

N,N- di- (m- methylphenyl)- 3,6- dimethyl- 1,4- dihydro- 1,2,4,5- tetrazine- 1,4- dicarboxamide

12/2017ZGDHu-1 for cancer therapy.
8/2016Induction of G2/M phase arrest and apoptosis by ZGDHU-1 in A549 and RERF-LC-MA lung cancer cells.
4/2015N,N'-di-(m-methylphenyi)-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboamide (ZGDHu-1) suppresses the proliferation of PANC-1 pancreatic cancer cells via apoptosis and G2/M cell cycle arrest.

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Jun Xia Research Topics

Disease

61Neoplasms (Cancer)
05/2022 - 07/2005
17Schizophrenia (Dementia Praecox)
12/2018 - 07/2008
15Pancreatic Neoplasms (Pancreatic Cancer)
03/2022 - 04/2012
10Lung Neoplasms (Lung Cancer)
01/2022 - 02/2015
9Infections
04/2019 - 10/2003
8Neoplasm Metastasis (Metastasis)
01/2022 - 05/2006
8Breast Neoplasms (Breast Cancer)
01/2017 - 01/2012
7Carcinogenesis
03/2022 - 12/2009
7Pain (Aches)
01/2021 - 10/2010
7Hypoxia (Hypoxemia)
12/2020 - 07/2012
6Inflammation (Inflammations)
01/2021 - 03/2006
6Psychotic Disorders (Schizoaffective Disorder)
12/2016 - 10/2009
5Mitochondrial Diseases (Mitochondrial Disease)
01/2021 - 01/2013
5Body Weight (Weight, Body)
01/2021 - 10/2003
5Melanoma (Melanoma, Malignant)
09/2019 - 06/2014
4Acne Vulgaris
10/2022 - 09/2018
4Neuralgia (Stump Neuralgia)
02/2022 - 02/2011
4Virus Diseases (Viral Diseases)
01/2022 - 12/2010
4COVID-19
01/2022 - 01/2020
4Non-alcoholic Fatty Liver Disease
01/2021 - 10/2017
4Dizziness (Lightheadedness)
01/2021 - 10/2016
4Osteoarthritis
10/2020 - 06/2014
4Prostatic Neoplasms (Prostate Cancer)
11/2019 - 05/2013
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 01/2018
3Carcinoma (Carcinomatosis)
01/2022 - 07/2005
3Hypertension (High Blood Pressure)
12/2021 - 03/2017
3Disease Progression
07/2021 - 10/2016
3Colitis
06/2021 - 02/2021
3Necrosis
01/2021 - 05/2006
3Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 03/2006
3Osteonecrosis (Kienbock's Disease)
11/2020 - 04/2018
3Obesity
10/2020 - 10/2019
3Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
12/2019 - 10/2017
3Glioma (Gliomas)
08/2019 - 10/2017
3Neurodegenerative Diseases (Neurodegenerative Disease)
03/2019 - 06/2010
3Autosomal Recessive 3 Severe Congenital Neutropenia
01/2018 - 01/2008
3Multiple Myeloma
01/2018 - 07/2010
3Leukemia
12/2017 - 05/2015
3Aortic Dissection
08/2017 - 03/2011
3Weight Gain
11/2016 - 05/2013
3Psychomotor Agitation (Akathisia)
07/2016 - 05/2013
2Hyperalgesia
02/2022 - 05/2021
2Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 05/2006

Drug/Important Bio-Agent (IBA)

29Proteins (Proteins, Gene)FDA Link
01/2022 - 03/2006
15Pharmaceutical PreparationsIBA
12/2021 - 07/2008
12Biological ProductsIBA
03/2022 - 05/2006
11Biomarkers (Surrogate Marker)IBA
01/2022 - 09/2007
10MicroRNAs (MicroRNA)IBA
10/2017 - 04/2012
9Antipsychotic Agents (Antipsychotics)IBA
11/2016 - 10/2009
8Messenger RNA (mRNA)IBA
01/2022 - 12/2009
8Phosphotransferases (Kinase)IBA
01/2022 - 03/2006
6Protein Kinases (Protein Kinase)IBA
01/2021 - 04/2009
6Arsenic Trioxide (Trisenox)FDA Link
01/2017 - 10/2011
5EnzymesIBA
01/2022 - 01/2013
4CurcuminIBA
06/2021 - 04/2011
4Small Interfering RNA (siRNA)IBA
05/2021 - 07/2016
4CytokinesIBA
01/2020 - 10/2003
4Glucose (Dextrose)FDA LinkGeneric
10/2019 - 09/2005
4AtrazineIBA
11/2018 - 01/2016
4GenisteinIBA
01/2016 - 12/2012
3RNA (Ribonucleic Acid)IBA
10/2022 - 01/2014
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2021 - 05/2006
3LipidsIBA
12/2021 - 06/2017
3Histones (Histone)IBA
06/2021 - 04/2015
3TeaIBA
03/2021 - 01/2021
3Dextran SulfateIBA
03/2021 - 01/2021
3Analgesics (Analgesic Drugs)IBA
01/2021 - 10/2016
3LycopeneIBA
01/2021 - 01/2016
3garcinolIBA
01/2021 - 11/2019
3nitidineIBA
12/2020 - 01/2019
3Oxygen (Dioxygen)IBA
12/2020 - 04/2015
3C-Reactive ProteinIBA
01/2020 - 04/2019
3Hemoglobins (Hemoglobin)IBA
01/2020 - 04/2008
3Methylphenidate (Ritalin)FDA LinkGeneric
12/2019 - 10/2017
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
03/2019 - 09/2007
3N-Methylaspartate (NMDA)IBA
03/2019 - 09/2007
3DNA (Deoxyribonucleic Acid)IBA
01/2019 - 09/2007
3Insulin (Novolin)FDA Link
01/2019 - 01/2013
3N,N- di- (m- methylphenyl)- 3,6- dimethyl- 1,4- dihydro- 1,2,4,5- tetrazine- 1,4- dicarboxamideIBA
12/2017 - 04/2015
3Risperidone (Risperdal Consta)FDA LinkGeneric
12/2016 - 10/2009
3GemcitabineFDA Link
01/2016 - 01/2014
3Clozapine (Clozaril)FDA LinkGeneric
01/2014 - 07/2008
3Leukocyte Elastase (Neutrophil Elastase)IBA
03/2011 - 12/2007
2Isotretinoin (Accutane)FDA LinkGeneric
10/2022 - 09/2018
2Glycoproteins (Glycoprotein)IBA
05/2022 - 01/2022
2UbiquitinIBA
03/2022 - 01/2017
2Oncogene Proteins (Oncogene Protein)IBA
03/2022 - 01/2019
2VaccinesIBA
01/2022 - 11/2021
2Immunoglobulin G (IgG)IBA
01/2022 - 01/2017

Therapy/Procedure

32Therapeutics
10/2022 - 01/2007
7Drug Therapy (Chemotherapy)
02/2022 - 01/2014
6Knee Replacement Arthroplasty (Total Knee Replacement)
02/2021 - 11/2012
6Radiotherapy
01/2019 - 05/2013
5Lasers (Laser)
09/2018 - 04/2014
4Arthroplasty
09/2021 - 06/2014
4Photochemotherapy (Photodynamic Therapy)
07/2021 - 01/2017
3Hearing Aids (Hearing Aid)
12/2018 - 10/2016
3Dance Therapy
10/2013 - 01/2009
3Cardiopulmonary Bypass (Heart-Lung Bypass)
06/2012 - 06/2008
2Immunotherapy
01/2022 - 06/2008